Abstract: The straddle-type monorail system may experience significant lateral deformation under limit states, which has been relatively less studied in the past. A novel isolation bearing for straddle-type monorails integrating a full section yield damper and a lead rubber bearing, is proposed in this study. Low-cyclic reversed loading tests were conducted under various compressive stresses and loading frequencies and the results were compared with numerical simulations. This paper focuses on the synergistic energy dissipation mechanism between full-section yield damper and lead rubber bearing and the influence of compressive stress and loading frequency on the equivalent stiffness, equivalent damping ratio and cumulative hysteretic energy dissipation of the bearing. The results show that this bearing has multi-stage energy dissipation characteristics, and a secondary stiffness hardening is realized during the loading process, providing yield reserve stiffness for the structure under limit states. The change of compressive stress is directly proportional to the change of the equivalent stiffness and energy dissipation capacity. When the compressive stress exceeds 2.5σ₀ （σ₀=2.12 MPa）, the growth rates of the equivalent stiffness and damping ratio of the bearing decrease. The increase of loading frequency has a minimal impact on the equivalent stiffness, equivalent damping ratio and cumulative hysteretic energy dissipation of the bearing. The results of numerical simulation are in good agreement with the test results, which can provide technical support for the promotion and application of this bearing.