Abstract: Pulsed Magneto-Oscillation (PMO) solidification homogenization technology is an original technology developed by the Advanced Solidification Technology Center of Shanghai University, which is used to solve the problems of microstructure refinement and homogenization during metal solidification. To further improve the continuous casting production level of SWRCH22A cold-heading steel of Angang Steel Co., Ltd., this technology was applied to its industrial production, and a series of industrial tests were carried out under different PMO process parameters. The results show that after the application of PMO technology, the central defects of continuous casting billets, such as centerline shrinkage cavities, centerline porosity and centerline carbon segregation, are effectively controlled. The ratio of samples with centerline shrinkage cavities, centerline porosity and centerline carbon segregation not higher than grade 0.5 reaches nearly 100%. The central equiaxed crystal ratio increases significantly with the increase of PMO parameters, with the maximum reaching 18.37%, and the proportion of equiaxed crystals reaches 26%. Meanwhile, PMO technology can significantly improve the radial carbon segregation of cast billets, and the improvement degree of centerline segregation increases with the increase of PMO parameters. When the PMO voltage is 290 kV, the centerline carbon segregation decreases from the original 0.245% to 0.20%, a reduction of 18.4%.