Abstract: To promote the digital transformation of enterprises and realize the whole-process dynamic management of laboratory equipment, this paper aims to solve the pain points existing in traditional equipment management, such as inadequate overall coordination, low utilization rate, insufficient information sharing, and incomplete process monitoring. With Web technology as the core architecture, combined with rule engines, multi-type databases, 3D rendering engines and other technical means, an information management system for laboratory equipment is constructed. The system realizes functions including integrated equipment scheduling, information sharing and query, real-time data collection and storage, remote monitoring, and digital twin visualization. It has significantly improved equipment utilization and management efficiency, achieved 24 h full monitoring of the test process, effectively reduced safety and quality risks in testing, and provided a feasible technical solution for the digital transformation of laboratories and the high-quality development of enterprises.