Abstract: Accurate determination of rare earth elements（REEs） in vanadium-titanium magnetite is essential for evaluating the resource potential of REEs in such ores. Samples were digested using an open-vessel digestion method with an HNO₃-HF-H₂SO₄ acid system. Instrumental conditions were optimized as follows: sampling depth of 3 mm, radio-frequency power of 1 350 W, and nebulizer gas flow rate of 1.05 L/min. The isotopes ⁸⁹Y, ¹³⁹La, ¹⁴⁰Ce, ¹⁴¹Pr, ¹⁴⁶Nd, ¹⁴⁷Sm, ¹⁵¹Eu, ¹⁵⁷Gd, ¹⁵⁹Tb, ¹⁶³Dy, ¹⁶⁵Ho, ¹⁶⁶Er, ¹⁶⁹Tm, ¹⁷²Yb, and ¹⁷⁵Lu were selected for determination. Interference equations were applied to correct for polyatomic ion interference on ¹⁵⁷Gd, ¹⁵⁹Tb, ¹⁶⁵Ho, ¹⁶⁶Er, and ¹⁶⁹Tm. The interference from high concentrations of Ti and Fe in the solution was also evaluated and compensated. A method for the determination of REEs in vanadium-titanium magnetite by open-vessel acid digestion-ICP-MS was established. Under the optimized conditions, the correlation coefficients of the calibration curves for all REEs were not less than 0.999 3. The limits of detection（LOD） ranged from 0.007 to 0.25 μg/g, and the limits of quantification（LOQ） were between 0.028 and 1.00 μg/g. The proposed method was applied to the determination of REEs in actual samples, yielding relative standard deviations（RSDs, n=6） of 0.85% to 3.6% for all elements. The similar REE distribution patterns observed for three vanadium-titanium magnetite samples from different mining areas in Chengde, Hebei Province, indicate they share a similar material source.